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Access to Compound Collection

Physical
Pricing/Discount Options: Call #2
Unique Identifier: 51dd342a-c5d6-48f8-8cd9-f3e0c364477e

Service Description

The Unit: Chemical Biology Consortium Sweden (https://www.scilifelab.se/units/cbcs/) The infrastructure is part of Science for Life Laboratory (SciLifeLab) which is an academic collaboration between Swedish universities (including Karolinska Institutet) and a national research infrastructure with a focus on life science. Chemical Biology Consortium Sweden (CBCS) is a national research infrastructure offering an extensive portfolio of services - from computational and organic chemistry to phenotypic small molecule screens in cells and model organisms, cell painting and functional precision medicine. The mission of CBCS is to provide a state-of-the-art platform and expertise for the generation of high-quality bioactive chemical tools (small organic molecules) for applications within life science research in general and with the ultimate goal to explore complex biology. Our units comprise compound handling labs (hosting the SciLifeLab Compound Collection of ca 350,000 molecules), screening labs (microtiter format liquid handling robotics and a wide range of plate readers), and chemistry labs (equipment and instrumentation for organic chemistry synthesis and analysis).

The service: Access to compound collection https://www.cbcs.se/the-compound-collection The Scilifelab Compound Collection is managed by the Compound Center at CBCS KI, and is based on donations of high-quality sets from the pharmaceutical industry (Biovitrum, Karobio, Orexo/Biolipox, KDev) and has been developed and expanded with compounds from various commercial compound vendors. The compounds can be readily available in assay-ready plates through acoustic nano-litre scale liquid dispensing or in 96-tube racks; compounds are stored at 10mM concentration in DMSO solution at - 20 °C under humidity control. We provide: o Management, storage, and processing of solids and liquids. o Compound delivery and interface with key customers. o Performance of instruments and automation that support these operations. o Analytical techniques used for quality assurance. o Sample informatics, including registration and compound quality data.

Offerings: Research & Development Scientific & Medical Communication Testing Laboratory (bioanalysis, wet lab, *-omics, etc.)
TEF-Health Use Case Domain: All
Provider Logo Service Logo

Provider & Contact

Provider Organisation Karolinska Institutet (KI)
Provider Country Sweden
Published Email tef-health@ki.se
Billing: per project
Full Price €Facility cost: 140EUR/hourPersonnel cost: 115EUR/hour
Reduced Price €Facility cost: 140EUR/ hourPersonnel cost 0-110 EUR/h
Pricing Detail

Prices are subject to change and are indicative only. Facility cost of 140EUR/hour cover administration time at the Compound Centre; for example, for a full screen (560 hours project), 20 hours were needed for compounds administration purpose. An additional fee of 6000EUR/ project is also added for gaining access to the compound library.

Only personnel cost (average cost of 115EUR/hour) can be subsidized up to 100% (depending upon affiliation) by TEF-Health.

Study case example of cost calculation for a whole project including access to compound collection, 20 hours administration time, and support on project management and screening expertise consultancy): Full price: 14 280 EUR, reduced price: 8 750EUR (subsidization of 40% in this example).

Operational Details

Dependencies & Restrictions Facility costs

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